Senior Researcher in Systems Biology of Microbial Metabolism – DTU Biosustain

Job title:

Senior Researcher in Systems Biology of Microbial Metabolism – DTU Biosustain

Company:

Danmarks Tekniske Universitet

Job description

Job Description:Are you ready to drive cutting-edge research in microbial metabolism? We are looking for a Senior Researcher like you to lead pioneering studies on microorganisms capable of utilizing one-carbon (C1) compounds.In this role, you will conduct groundbreaking research in microbial physiology and metabolism using a systems biology approach. Your work will generate deep insights into microorganisms of industrial significance. Your primary objective will be to develop a comprehensive systems-level understanding of these microbes, leveraging multi-omics data and advanced computational models.Additionally, you will apply these insights to engineer high-performance microbial bio-factories for the efficient conversion of C1 compounds into valuable products.Responsibilities and qualifications
Despite decades of research, many aspects of microbial metabolism remain to be fully understood. This is particularly true for environmental microorganisms capable of utilizing C1 compounds-an area with immense potential but limited prior study.In this role, you will lead pioneering research to deepen our understanding of microbial physiology and metabolism. Using a multi-disciplinary approach, you will generate and analyze large-scale datasets-including high-quality multi-omics and physiological data-to drive biotechnological advancements. Additionally, you will develop novel methodologies for data integration and modeling, ultimately informing and directing engineering efforts in microbial systems.Key Responsibilities:

• Supervise and mentor a diverse team of wet lab and dry lab scientists, fostering a collaborative research environment.
• Lead cutting-edge research in systems biology to decode microbial metabolism.
• Develop and implement novel analytical, cultivation, and computational methods.
• Oversee and expand a state-of-the-art laboratory equipped with mass spectrometers, plate readers, bioreactors, and other advanced instrumentation.
• Secure research funding by conceptualizing and writing compelling grant proposals.
• Disseminate impactful findings through high-impact publications and presentations at international conferences.

This position offers the opportunity to work at the forefront of microbial systems research, contributing to groundbreaking discoveries with real-world applications in biotechnology.You must contribute to teaching at the Department. DTU employs two working languages: Danish and English. You are expected to be fluent in at least one of these languages, and in time are expected to master both.Specific Qualifications:

• Proven expertise in microbial systems and synthetic biology, with a strong international research track record.
• Demonstrated leadership in managing, mentoring, and supervising research staff, as well as MSc and PhD students.
• Extensive experience in project management, strategic planning, and effective budgeting.
• Innovative in technology development, with a strong background in designing and implementing novel methodologies.
• Excellent collaboration and communication skills, with the ability to work effectively in multidisciplinary teams and present research to diverse audiences.
• Broad microbial expertise, including experience working with multiple microbial species, particularly C1-assimilating microorganisms.
• Hands-on proficiency in analytical chemistry, including LC-MS/MS targeted metabolomics, GC-MS, and HPLC.
• Computational expertise, including programming, multi-omics data analysis (metabolomics, fluxomics, transcriptomics, proteomics), data integration, and metabolic modeling.
• Firsthand experience in molecular biology and genetic engineering.
• Practical experience in automation and small-scale fermentations, including gas fermentation.

As a formal qualification you must hold a PhD degree (or equivalent) as well as academic qualifications equivalent to those obtained by holding a position as a researcher or postdoc. To be appointed as a senior researcher, you must have completed a didactic/pedagogic education. If you do not have the necessary education, then it is possible to complete this requirement within a period of two years of appointment.You will be assessed against the responsibilities and qualifications stated above and the following general criteria:

• Research experience
• Experience and quality of teaching
• Research vision and potential
• International impact and experience
• Societal impact
• Innovativeness, including commercialization and collaboration with industry
• Leadership, collaboration, and interdisciplinary skills
• Communication skills

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.You can read more about career paths at DTU .Starting date is 01-08-2025 (or according to mutual agreement). The position is a full-time position.Further information
Further information may be obtained from Scientific Director Lars Keld Nielsen .You can read more about DTU Biosustain atIf you are applying from abroad, you may find useful information on working in Denmark and at DTU at .Application procedure
Please submit your online application no later than 21 April 2025 (23:59 Danish time).Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

• Application (cover letter)
• Vision for teaching and research
• CV including employment history, list of publications indicating scientific highlights, H-index and ORCID (see

) including documentation of teaching experience * Academic Diplomas (MSc/PhD)You can learn more about the recruitment process .Applications received after the deadline will not be considered.All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position.The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain)
Recent progress in our ability to read and write genomic code, combined with advances in automation, analytics and data science, has fundamentally changed the scope and ambition of harnessing the potential of biological systems. Big data approaches and analysis of biological systems are key research instruments at the Center. DTU Biosustain utilizes these advances for microbial cell factory design to foster sustainable lifestyles in relation to three application areas: Sustainable Chemicals, Natural Products, and Microbial Foods.Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

Expected salary

Location

Kongens Lyngby, Hovedstaden – Lyngby, Midtjylland

Job date

Thu, 20 Mar 2025 05:25:46 GMT

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