Senior Lead ADME

Job title:

Senior Lead ADME

Company:

headcount AG

Job description

The Senior Lead ADME will join the Early Development group to support drug development. This role manages outsourced nonclinical studies from lead optimization to clinical development, leveraging expertise in absorption, distribution, metabolism, and excretion. Responsibilities include designing, overseeing, and interpreting in vitro and in vivo ADME studies, communicating outcomes, managing timelines, and ensuring accurate reporting.The Senior Lead will work closely with and report to the Head of ADME.Responsibilities:

• Lead and execute non-clinical ADME/PK studies to support the characterization of pre-clinical and clinical compounds.
• Develop and implement ADME/PK strategies, including selecting and outsourcing studies to external vendors/CROs.
• Take ownership: Design, optimize, and review study plans aligned with project goals and ADME strategy.
• Collaborate closely with CROs, team members, and management to review and finalize study reports. Interpret and integrate ADME/PK data from external partners; present findings to cross-functional teams.
• Contribute ADME/PK sections to key regulatory documents such as investigator brochures, IND/IMPDs, CTAs, and NDAs.

Requirements:

• PhD in life sciences with postdoctoral training preferred.
• Minimum of 7 years of industry experience in ADME/PK studies.
• Strong background in small molecule drug development; expertise in bioanalysis (LC-MS) is advantageous.
• Proven track record in contributing to successful transitions of drug candidates into clinical development.
• Familiarity with regulatory requirements and guidelines in drug development.

3.5

Expected salary

Location

Nederland

Job date

Thu, 27 Jun 2024 22:55:36 GMT

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