Senior Associate Scientist Tuberculosis Discovery in Antwerp, Belgium

Senior Associate Scientist Tuberculosis Discovery – 2406198655W

Description

About Johnson & Johnson

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.

The Johnson & Johnson Communicable Disease Unit is committed to discover and develop novel antibiotics for tuberculosis and build on the legacy of bedaquiline, a groundbreaking drug developed by Janssen for multidrug-resistant tuberculosis (MDR-TB). Tuberculosis is the leading cause of death from a single pathogen and the biggest contributor to AMR-related death worldwide. At Communicable Disease, we take a multi-disciplinary approach to develop new antimycobacterial and technologies that would help to achieve simpler, shorter and safer treatment regimens for MDR-TB patients.

We are looking for a self-motivated, enthusiastic and innovative scientist, to join our dynamic Discovery-Translational team in Beerse, Belgium.

The Associate Scientist will mainly develop, conduct and manage in vitro assays/ in vivo models for M. tuberculosis to evaluate the efficacy of new anti-tuberculosis compounds, alone and in combination. They will also help to manage key interactions with external stakeholders. This is all done in a team-oriented, result driven, international research environment that provides an excellent career opportunity for a Scientist that takes initiative in driving the Communicable Disease strategy forward.

Job Responsibilities:

• Develop, optimize, validate and perform novel in vitro assays for M. tuberculosis .

• Perform and report on M. tuberculosis MIC, MBC and kill kinetic assays.

• Conduct and report on in vivo pharmacokinetic/pharmacodynamic studies.

• Maintain bacterial and compound stocks, and the shipment of these to external stakeholders.

• Act as operational lead and point of contact for the TB in vitro and in vivo facilities.

• Establish a key understanding of the relevance of the data being generated.

• Present own work to internal and external stakeholders.

• Write up lab book to department and patent-acceptable standard.

• Use appropriate scientific literature to plan assays.

• Maintain awareness of the relevant scientific literature and contemporary laboratory practices.

Qualifications

The following are minimum requirements related to the Senior Associate Scientist position.

• MSc in a relevant Biotechnology, Microbiology, Biochemistry or related; with at least 2 years of experience in industry setting or equivalent.

• Experienced in different microbiology techniques, such us culture, stocks mainteinance, molecular techniques and compound efficacy assessment. Work experience with mycobacteria would be a plus.

• Experience working in a Biosafety level 3 is preferred.

• Lab experience working with mice and having the corresponding accreditation (FELASA B).

• Proficient in English.

• Proficient in MS Office and Graphpad Prism.

• Demonstrated ability to analyze and interpret data and reporting the results.

• Demonstration of robust oral and written communication skills. Shown ability to collaborate, empathize with team members of different backgrounds required.

• Ability to work well in a quick paced, dynamic and interactive environment is vital. Excellent interpersonal skills and ability to work under pressure.

Johnson & Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Primary Location Europe/Middle East/Africa-Belgium-Antwerp-Beerse

Organization Janssen Pharmaceutica N.V. (7555)

Job Function Biological Research

Req ID: 2406198655W