Job title:
Researcher position (role in the project: Senior postdoctoral researcher)
Company:
Job description
Offer DescriptionRecruitment for the project “RNA and Cell Biology Platform for Research and Innovation in Medicine (RACE-PRIME)” (grant agreement no. FENG.02.01-IP.05-T003/23) implemented within the framework of the International Research Agendas funded by the European Funds for Smart Economy programme, for the position of Senior postdoctoral researcherto carry out research work in the cell biology area under the direction of Prof. Marta Miączyńska, head of the Laboratory of Cell Biology at the International Institute of Molecular and Cell Biology in Warsaw ( ), in collaboration with Prof. Matthias Bochtler (Laboratory of Structural Biology).The aim of RACE-PRIME is to establish IIMCB as a world-class Center of Excellence in RNA and Cell Biology. The goal of RACE-PRIME is to translate basic research findings, e.g., for developing new therapies, diagnostic methods, discovering new therapeutic targets, or identifying molecules with desired properties to be developed into drugs.Description of the project area: KMT2/MLL proteins meditate positive epigenetic memory, by keeping H3K4 tri- and mono-methylation at promoters and enhancers. Germ-line loss of the enhancer directed KMT2D causes a developmental disorder, Kabuki syndrome. Somatic loss of KMT2C and KMT2D is a common occurrence in a broad spectrum of cancers, presumably because functional plasticity favors malignancy.Where to apply E-mail[email protected]RequirementsResearch Field Biological sciences » Biology Education Level PhD or equivalentResearch Field Chemistry » Biochemistry Education Level PhD or equivalentSkills/QualificationsJob description: The successful candidate will work on KMT2/MLL proteins and their role in positive epigenetic memory. The candidate will participate in (a) tests of a little-studied chromatin mark as the possible anchor for KMT2 proteins, (b) test developmental consequences of a loss of chromatin reader function of KMT2s in WT and mutant embryoid bodies using single cell transcriptomics, and (c) participate in a planned collaboration with the Canadian Structural Biology consortium on a small molecule screen for compounds that stabilize positive epigenetic memory for KMT2 proteins that have fold-destabilizing loss-of-function mutations.Specific RequirementsRequirements: * PhD in biological sciences or related field.
- Minimum of 5 years of experience in research and development. At the same time, the period of 5 years is counted from the year of obtaining the doctoral degree.
- Minimum 5 years of documented laboratory experience in molecular and cellular biology after Ph.D.
- Experience with cell culture, embryoid bodies and chromatin-mapping techniques (CHIP-Seq, CUT&RUN, greenCUT&RUN).
- Experience with zebrafish would be an asset.
- Independence, commitment, initiative, teamwork skills.
- Proficiency in spoken and written English.
- Ability to write and edit publications in English.
- Scientific track record documented by publications in international journals.
Languages ENGLISH Level GoodResearch Field Biological sciences » BiologyChemistry » Biochemistry Years of Research Experience 4 – 10Additional InformationBenefitsWe offer: * Full-time employment contract, initially for a period of 6 months with the possibility of extension.
- Competitive salary ranging from 9 800 PLN gross/month to 11 400 PLN gross/month (depending on experience).
- Attractive benefits package including subsidization for MultiSport card and medical insurance.
- Full technical, administrative, and organizational support in Polish and English from professional staff.
- Opportunity to participate in courses, conferences, scientific training, and substantive support from colleagues.
Eligibility criteriaSelection criteria: * Technical competencies, experience and alignment of specialized knowledge with the position.
- Scientific achievements – publications, awards, grants, etc.
- Soft skills – proficiency in English, motivation letter, communication skills, teamwork ability, alignment of individual development plans with project goals.
Selection processCandidates will be selected through an open competition, in accordance with the principles set out in the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers, which are part of the HR Excellence in Research strategy.Additional commentsHow to apply: * Please send your applications to the email address:
- In the email subject line, please include the following information: “CELL 6 Researcher MAB” followed by your first and last name.
- Applications should be submitted in English. The application should include a CV, list of publications, a motivation letter describing key scientific achievements, and contact details (email and phone number) of at least two potential referees, including your direct supervisor.
- Please include the following statement in your CV: “I hereby give consent for my personal data included in the application documents to be processed by the International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, 02-109 Warsaw, for the purpose of carrying out the recruitment process.” Full information is available at
.The competition may be extended until a candidate meeting all requirements is found. Website for additional job detailsWork Location(s)Number of offers available 1 Company/Institute International Institute of Molecular and Cell Biology in Warsaw Country Poland Postal Code 02-109 Street ks. Trojdena 2 GeofieldContact CityWarsaw WebsiteStreet4, Ks. Trojdena Postal Code02-109 E-Mail[email protected]STATUS: EXPIREDShare this page
Expected salary
Location
Warszawa, mazowieckie
Job date
Fri, 12 Jul 2024 23:35:17 GMT
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