Job title:
Postdoctoral scientist
Company:
Job description
Offer DescriptionProject title: Role of GAB glutaminase in glioblastoma.Department of Neurotoxicology, Mossakowski Medical Research Institute Polish Academy of Sciences is recruiting to the NCN OPUS 21 project entitled „Role of GAB glutaminase in glioblastoma” (2021/41/B/NZ5/01883).Leader: dr hab. Monika SzeligaThe project:A growing body of evidence suggests that GAB glutaminase acts as a tumor suppressor. Our previous studies clearly indicate that: i) glioblastoma (GBM), the most malignant glial tumor, lacks GAB; ii) transfection of GBM cells with a GAB sequence inhibits their survival, proliferation, migration, and sensitizes them to oxidative stress and temozolomide, a first-line chemotherapeutic agent for GBM.The main objective of this project is to elucidate the molecular determinants of tumor-suppressive properties of GAB observed in GBM cells and examine the influence of GAB transfection on the phenotype of GBM cells in in vivo settings. The main hypothesis of this project, supported by preliminary results and data from the literature, is that transfection with a GAB sequence suppresses malignant phenotype of GBM cells by modulation of the transcriptome/miRNome and/or proteome of these cells. Results from this project will enrich the existing knowledge about the role of GAB in GBM cells.Skills/Qualifications1. PhD Degree (or equivalent) in bioinformatics, biology, biotechnology or related fields.2. Experience in the analysis of multi-omics data3. Scientific achievements documented by publications4. Very good command of English and practice in scientific writing/presentation of scientific data in English5. Communication skills, openness to new challenges, very good organization of laboratory work, creative and analytical thinking6. Experience in experimental work in a molecular laboratory will be an additional advantageSpecific RequirementsThe post-doc will be responsible for:
- analysis and interpretation of multi-omics data;
- present results at team meetings, seminars and conferences, and through scientific publications;
- supervise students engaged in the project;
Contract type: work agreement, full-timeContract length: up to 18 months, start 01 October 2024Salary: Gross salary (total employment cost) of 10 000 PLN/month (total employment cost is the gross/gross amount including employer’s expense, social and health insurances)RequirementsResearch Field Biological sciences » Other Education Level PhD or equivalentSkills/Qualifications1. PhD Degree (or equivalent) in bioinformatics, biology, biotechnology or related fields.2. Experience in the analysis of multi-omics data3. Scientific achievements documented by publications4. Very good command of English and practice in scientific writing/presentation of scientific data in English5. Communication skills, openness to new challenges, very good organization of laboratory work, creative and analytical thinking6. Experience in experimental work in a molecular laboratory will be an additional advantageSpecific RequirementsThe post-doc will be responsible for:
- analysis and interpretation of multi-omics data;
- present results at team meetings, seminars and conferences, and through scientific publications;
- supervise students engaged in the project;
Languages ENGLISH Level ExcellentResearch Field Biological sciences » Other Years of Research Experience 4 – 10Internal Application form(s) neededHow to apply.pdfEnglish(75.1 KB – PDF)Additional InformationWork Location(s)Number of offers available 1 Company/Institute Mossakowski Medical Research Institute, Polish Academy of Sciences Country Poland City Warsaw Postal Code 02-106 Street 5 Pawinskiego StreetWhere to apply E-mail[email protected]Contact CityWarsaw WebsiteStreet5 Pawinskiego Street Postal Code02-106STATUS: EXPIRED
Expected salary
Location
Warszawa, mazowieckie
Job date
Thu, 30 May 2024 04:51:53 GMT
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