Postdoctoral Researcher position in the Laboratory of Cellular Proteostasis

Job title:

Postdoctoral Researcher position in the Laboratory of Cellular Proteostasis

Company:

Job description

Postdoctoral Researcher position in the Laboratory of Cellular ProteostasisThe newly created Laboratory of Cellular Proteostasis at the International Institute for Molecular and Cell Biology in Warsaw (IIMCB) /, Warsaw, headed by Dr. Lidia Wróbel, seeks a motivated Postdoctoral Researcher to join the project entitled “Nuclear protein quality control in neurodegeneration” carried out as the Sonata project (2023/51/D/NZ3/01939) financed of the National Science Centre, Poland. The project aims to understand the mechanisms governing mammalian nuclear protein quality control (PQC) with primary focus on protein clearance pathways and its relevance in human diseases.The deadline for applications is 31.08.2024. Start of employment 01.10.2024 or later.As a Postdoctoral Researcher you will be responsible for: performing a CRISPR/Cas9-based high-throughput screen to find novel factors and pathways key for protein quality control maintenance and ubiquitin-proteasome system (UPS) in the mammalian nucleus. In the project you will use cell culture methods (including human induced pluripotent stem cell (iPSC)-derived neurons), biochemical and molecular biology methods, flow cytometry and confocal microscopy. You will be responsible for planning and conducting experiments, recording the experiments in electronic lab notebook, data analysis and regular reporting of the results.Requirements:

• Hold a PhD degree in Biology, Biotechnology, Medicine or equivalent field. Candidates with degrees in other fields including Engineering, Computer science, Physics will also be considered if they have relevant experience.
• Fulfill the requirements of the competition

(section 2.1.1) * Excellent written and oral communication skills in English

• High motivation and proactive and collaborative attitude

Previous experience in one or more methods mentioned below is desirable (but not prerequisite):

• CRISPR/Cas9-based high-throughput screening
• Cell culture (cell lines, (iPSC)-derived neurons, CRISPR-based cell line modification techniques)
• Confocal microscopy
• Flow cytometry and cell sorting

We offer:

• Full employment contract initially for 6 months, with the extension up to 36 months
• Gross monthly remuneration approx. 8700 PLN/month (the final monthly gross salary will be calculated individually during the employment process, taking into account the length of service).
• Additional bonuses such as the 13th salary after working for the Institute for six months in a given calendar year, or a Christmas bonus may supplement this salary.

• A friendly working atmosphere in an international environment
• Interesting scientific projects
• Position with 100% focus on research (no teaching obligations)
• Benefits including reduced-rate for an individual medical care package and membership in MultiSport program
• Full technical, administrative and organizational support from professional English-speaking personnel
• Opportunities for professional development – participation in courses, foreign conferences, funding for postgraduate studies, assistance in submitting your own grants.

How to apply:

• Apply now to
• In the subject include “Postdoc Sonata Wrobel” and your first and last name.
• Your application must be submitted in English and should contain one file including:

• CV (including list of publications and list of skills)
• motivation letter (including description of your key achievements, max one page)
• contact information to 2-3 people who can evaluate you (such as your thesis supervisor, academic advisor)
• Please include the following statement in your CV: “I hereby agree to the processing of my personal data, included in the application documents by the International Institute of Molecular and Cell Biology in Warsaw, 4 Księcia Trojdena Street, 02-109 Warsaw, for the purpose of carrying out the current recruitment process.”

Your personal data will be processed for the purpose of the recruitment procedure by the International Institute of Molecular and Cell Biology in Warsaw. Full information is available .Candidates will be selected in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy.If you have questions about further details, please emailIn case we do not find suitable candidate, application deadline will be postponed.

Expected salary

Location

Warszawa, mazowieckie

Job date

Sat, 20 Jul 2024 22:21:32 GMT

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