Postdoctoral researcher (M/F) – Microbiota and Alzheimer’s disease

Job title:

Postdoctoral researcher (M/F) – Microbiota and Alzheimer’s disease

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Job description

Offer DescriptionIn close collaboration with M. Cissé’s team in Nantes and as part of the ANR MICROCONNECT programme, this project will address the question of a causal relationship between dysbiosis and amyloid pathology on the one hand, and Alzheimer’s disease symptoms and digestive comorbidity on the other, with the aim of identifying the bacterial mediators involved and deciphering their mechanisms of action. This project could pave the way for innovative treatments targeting the intestinal microbiota or downstream molecular partners.

• Supervise a research project
• Design and perform experiments, including experimentation on mouse models (gavage, i.p. injections, blood sampling, oral and fecal microbiota sampling), behavioral testing, post-mortem neuropathology assessment, development and implementation of new experimental paradigms
• Analyze multi-omics data generated by CROs and platforms and correlate them with biological data.
• Analyze results and ensure their validity.
• Present results in the form of reports, posters or seminars.
• Write and update technical protocols, guarantee their follow-up and quality, keep a rigorous laboratory notebook.
• Write publications
• Contribute to the scientific and technological monitoring of the field of activity and its dissemination within the team
• Ensure the supervision and training of students and engineers
• Participate in the team’s collective tasks

The Institute of Functional Genomics (IGF) is a multidisciplinary CNRS-INSERM-University of Montpellier Joint Research Unit whose research programmes cover the fields of neuroscience, physiology and cancer biology.
The IGF is home to around 350 people – researchers, teacher-researchers, engineers, technicians, postdoctoral students and students – working in 23 research teams, 8 technology platforms and research support services.
The candidate will work under the supervision of Dr. S. Claeysen in the ‘Neuroproteomics and Signalling of Brain disorders’ team led by Philippe Marin. When he takes up his new post, the team will comprise 7 researchers, 1 clinician, 3 ITAs, 2 post-docs and 6 PhD students.
The project is part of the ANR MICROCONNECT
( ).In addition to its enriching environment, the CNRS offers the following benefits:
– 44 days’ leave and RTT with the possibility of acquiring 2 days for splitting, i.e. a maximum of 46 days
– partial reimbursement of home/work public transport costs
– possibility of benefiting from the sustainable mobility package
– reimbursement of supplementary health insurance costs up to €15 per month, subject to conditions
– low-cost canteen
– car parking
– leisure, sports and cultural offers via the CNRS social action and mutual aid committee (CAES) or local social action committees (CLAS).We are looking for a proactive person who can work both independently and in interaction with team members/consortium partners, ideally someone with experience of handling microbiota and animal models.Where to apply WebsiteRequirementsResearch Field Neurosciences Education Level PhD or equivalentResearch Field Biological sciences Education Level PhD or equivalentLanguages FRENCH Level BasicResearch Field Neurosciences Years of Research Experience NoneResearch Field Biological sciences Years of Research Experience NoneAdditional InformationEligibility criteriaProfile:
PhD in biology, neurobiology, microbiology or a related discipline.
Previous experience in animal experimentation is essential.
Experience in microbiota research would be highly appreciated.
Knowledge of immunology or neuroinflammation will be valuable.
A good understanding of bioinformatics and modelling models would be a plus.Character traits and work ethic:
Scientific rigor in the design of experiments and statistical analyses.
Autonomy, organization and responsiveness in a fast-paced environment with a heavy workload.
Ability to work independently while fostering team spirit.
Strong communication skills to interact proactively with colleagues and foster an interdisciplinary environment.
Excellent writing skills (reports, presentations, posters, manuscripts).
Fluency in spoken French or English is mandatory.Additional comments– Working with live animals
– Handling chemicals
– Handling sharp objects
– Working in a confined environment with restricted access
– Biosafety constraints (possession of domestic animals such as rodents not compatible with experiments)
– Work on screens
– Possible variations in working hours Website for additional job detailsWork Location(s)Number of offers available 1 Company/Institute Institut de génomique fonctionnelle Country France City MONTPELLIER GeofieldContact CityMONTPELLIER WebsiteSTATUS: EXPIREDShare this page

Expected salary

Location

Montpellier

Job date

Wed, 01 Jan 2025 06:47:30 GMT

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