Postdoctoral Fellowship in Transcriptional Regulation of Adipocyte Lineage Determination

Job title:

Postdoctoral Fellowship in Transcriptional Regulation of Adipocyte Lineage Determination

Company:

Syddansk Universitet

Job description

Job Description:The Mandrup group invites applications from outstanding candidates who are interested in joining our group as a postdoctoral fellow to help us understand the detailed molecular mechanisms regulating adipocyte lineage determination. Our group is based at the Functional Genomics & Metabolism Research Unit, Department of Biochemistry and Molecular Biology, SDU.Research project
Adipogenesis is the process by which stromal progenitor cells of the mesenchymal lineage develop into lipid-laden adipocytes. The efficiency of this process is of major biomedical importance, as it is required for the development of well-functioning adipose tissue, as well as for the healthy expandability of adipose tissue. Furthermore, the fact that this process can be efficiently induced in vitro makes adipogenesis an excellent model system for studying the functional genomics of stem cell differentiation, including the basic mechanisms of enhancer function and enhancer-opathies.The Mandrup group has a long-standing interest in the detailed molecular mechanisms governing transcriptional control of adipocyte differentiation. We apply a variety of sequencing-based, computational and molecular technologies, combined with loss- and gain-of-function strategies to study the mechanisms and role of the 3D chromatin architecture, the crosstalk between enhancers in enhancer communities and the role of specific transcription factors.As a postdoctoral fellow in the group, you will define your own project within the broader scope of transcriptional regulation of adipocyte differentiation. You will work closely together with other postdoctoral fellows and PhD students in the Enhancer subgroup on a daily basis, and you will also be expected to collaborate with colleagues in and , both directed by Susanne Mandrup. Furthermore, you will be able to benefit from the many international collaborations of our group, including our close collaboration with the Broad Institute in the framework of the .The Functional Genomics & Metabolism Research Unit
The is located in the , at , SDU. The research unit currently hosts nine independent research groups focusing on various aspects of gene regulatory mechanisms controlling cellular identity, differentiation, and metabolism. The research unit constitutes an international, ambitious, highly dynamic, and well-equipped working environment. The unit and the department have state-of-the-art facilities for next generation sequencing, single-cell transcriptomics, flow cytometry, mass spectrometry, metabolomics, bioimaging and transgenic mouse work. Strategic research alliances exist with Odense University Hospital (OUH).Qualifications/requirements
We are looking for a highly motivated, dedicated, and ambitious candidate with:

• A PhD degree in Life Science, preferably Molecular Biology, Biomedicine, or Computational Biology
• Experience with research in the field of transcriptional regulation
• Documented experience with cell biology and NGS data analysis
• At least one first-author publication or publication-grade manuscript in a relevant journal in the field
• Strong communication and collaborative skills and a desire to work in an interdisciplinary environment
• Proficiency in spoken and written English.

We offer:

• A three-year postdoc position in a stimulating and supportive, international research environment
• Training in a wide range of skills including leadership, research management, communication, networking, presentations, writing of grants and manuscripts etc.
• Mentoring and career development
• Access to state-of-the-art equipment, facilities, and infrastructure
• Opportunity to interact with an extensive network of national and international collaborators
• A competitive salary and social benefits (e.g. health coverage, parental leave, social security etc.)
• Dedicated assistance and support with various practical, social, and legal aspects (housing, visa, administration, tax etc.), especially for international candidates through our international staff office (ISO) and department.

For further information please contact Professor Susanne Mandrup ( ).Application, salary etc.
The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on (only available in Danish) and .The application must include the following:

• A curriculum vitae including information on previous employment.
• A full list of publications stating the scientific publications on which the applicant wishes to rely.
• Copy of PhD diploma.

Shortlisting may be used in the assessment process.Incomplete applications and applications received after the deadline will neither be considered nor evaluated.To qualify you must have passed a PhD or equivalent. Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.Applications must be submitted electronically using the link “Apply now”. Attached files must be in Adobe PDF format. We strongly recommend that you read before you apply.for international applicants about entering and working in Denmark.

Expected salary

Location

Odense, Syddanmark

Job date

Fri, 09 Aug 2024 23:32:33 GMT

To help us track our recruitment effort, please indicate in your email/cover letter where (vacanciesineu.com) you saw this job posting.