Postdoctoral fellow to study the hematopoietic stem cell niche in leukemia

Job title:

Postdoctoral fellow to study the hematopoietic stem cell niche in leukemia


Job description

Offer DescriptionThe Department of Hematology at the Erasmus Medical Center Cancer Institute runs an ambitious and internationally recognized research program in the field of bone marrow failure and leukemia. The overall goal of our laboratory is to gain a better understanding of the cellular elements and molecular pathways driving leukemogenesis. Specifically, we aim to understand the interplay between the bone marrow immune-microenvironment and hematopoietic stem/progenitor cells in this process.The postdoctoral projects will focus on dissecting the role of inflammatory signaling in the stem cell niche in malignant transformation in the hematopoietic system. We will exploit mouse modeling and state-of-the art (single-cell) molecular tools and strive to translate insights to human disease, exploring therapeutic modalities aimed at targeting inflammatory niche signaling in the immune-microenvironment to treat and prevent leukemia.Where to apply WebsiteRequirementsSpecific RequirementsThe position should appeal to scientists who want to perform cutting edge basic/translational research applying in vitro and in vivo modeling with the ultimate goal to develop novel therapeutics. The following skills and qualifications are required:

  • Demonstrated track record in basic/translational research (at least one publication with impact).
  • Excellent oral and written communication skills in English.
  • High level of motivation and ability to work in a team.

Expertise in hematology, immunology and/or stem cell biology, bio-informatical analyses of single cell data and mouse modeling would be highly recommendable. Being able to present a certificate of good conduct is a condition for the appointment.Additional InformationBenefits

  • The gross monthly salary amounts a maximum of € 6.402,- (scale 11), depending on your level of educacation and relevant experience, based on a full-time working week of 36 hours.
  • You will receive a contract for 1 year.
  • Excellent fringe benefits, such as a 13th month that is already paid out in

November and an individual travel expense package. * Pension insurance with ABP, we take care of approximately 2/3 of themonthly contribution. * Special benefits, such as an incompany physiotherapist and bicyclerepairer. There is also a gym where you can work on your fitness after work. * An
which aids you in preparing for your arrival and stay.Selection processFor more information about this position please contact: Marc Raaijmakers, Professor, .Additional commentsFor more information about this position please contact: Marc Raaijmakers, Professor, . Website for additional job detailsWork Location(s)Number of offers available 1 Company/Institute Erasmus MC Country Netherlands City Rotterdam Postal Code 3015 GD Street Dr. Molewaterplein 40Contact CityRotterdam WebsiteStreetDr. Molewaterplein 40 Postal Code3015 GDSTATUS: EXPIREDShare this page

Expected salary

€6402 per month


Rotterdam, Zuid-Holland

Job date

Sun, 09 Jun 2024 23:52:53 GMT

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