Postdoc Computational Modeling for Drug Safety Prediction
Offer DescriptionDo you have a passion to understand how biological networks are influenced by chemicals or drugs? Are you an expert in the development of computational models, with the application in mind of comparing such models to real-world biological data? As part of our enthusiastic and diverse team of mathematicians/ data scientists/ biologists you will employ computational dynamical modelling approaches in order to support drug safety prediction. Within our team at the Leiden Academic Centre for Drug Research ( ) we are looking to hire a postdoctoral researcher to develop such novel ways for drug safety prediction.Project description and key responsibilities
Human exposure to chemicals and drugs can result in responses of biological pathways ultimately resulting in organ-specific toxicities, e.g., liver failure. We urgently need strategies that can predict such toxicities. The primary aim of this postdoctoral project is therefore to predict drug-induced toxicities by utilizing mathematical models of cellular networks involved in resolving molecular stress and models describing the kinetics of compounds of interest. The models will be based on and fitted to various experimental data quantifying gene expression and cellular responses. Ultimately, such data-driven mechanistic models will describe activity within stress pathways and predict in vivo adversity of chemicals based on this activity.Key responsibilities
RequirementsSpecific RequirementsSelection criteria
Additional InformationBenefitsWe offerA fully funded one year postdoctoral position in the vibrant and top edge environment of the Leiden Academic Centre for Drug Research. The position is available from the summer of 2024 onwards.You will be appointed in accordance with the Collective Labour Agreement for Dutch Universities. The salary ranges from € 3.226 – € 5.090 gross per month, depending on experience (pay scale 10, ).Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3 %), training and career development. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. For international spouses we have set up a dual career programme. Candidates from outside the Netherlands may be eligible for a substantial tax break. For more information, see .Diversity and Inclusion
Fostering an inclusive community is a central element of the values and vision of Leiden University. Leiden University is committed to becoming an inclusive community which enables all students and staff to feel valued and respected and to develop their full potential. Diversity in experiences and perspectives enriches our teaching and strengthens our research. High quality teaching and research is inclusive.
Additional commentsDo you have questions about this position?Please contact Dr. Joost Beltman, Associate Professor, .You can find more information about the faculty of Science at . For more information about working at Leiden university please visit . Website for additional job detailsWork Location(s)Number of offers available 1 Company/Institute Universiteit Leiden Country Netherlands City Leiden Postal Code 2311EZ Street Rapenburg 70 GeofieldWhere to apply WebsiteContact CityLeiden WebsiteStreetRapenburg 70 Postal Code2311 EZSTATUS: EXPIRED
€3226 – 5090 per month
Leiden, Zuid-Holland
Thu, 04 Apr 2024 04:26:29 GMT
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