Post-doc bioinformatics
Offer DescriptionIn a project funded by the Netherlands Lung Foundation, we investigate lung growth up to peak lung function in early adulthood in the national birth cohort PIAMA (Prevention and Incidence of Asthma and Mite Allergy). This unique cohort investigates over 4,000 children from birth into early adulthood. We aim to understand what determines lung growth, as low lung function is a risk factor for COPD and collected data on nasal epigenome, and blood metabolome. If the candidate is successful, we will offer a second position (2 years) funded by a VICI scholarship to professor Koppelman, where we investigate asthma development in childhood by mul-omics analysis, including single cell RNA sequencing and DNA-methylation.
Integrative multi-omics is a central part of activities, and GRIAC investigators have leading roles in single cell transcriptome sequencing, genome sequencing, epigenetic and integrative multi-omics studies of asthma, allergy, and COPD. We lead international research consortia, and have a strong portfolio of academic and industrial collaborations. We incorporate methods from artificial intelligence in our research and are able to train you in innovative methods.The candidate is expected to
– Perform epigenetic analysis of nasal DNA methylation and lung growth.
– Integrate these data with other ‘omic’ layers, including genetic variation, and gene expression, at two different timepoints using machine learning.
– Participate in the National PIAMA consortium, as well as international collaborations.
– Contribute to the training and supervision of PhD students in our department.Where to apply WebsiteRequirementsSpecific RequirementsWe are looking for an enthusiastic and ambitious computational biologist / bioinformatician with an PhD in computational biology, bioinformatics or an adjacent relevant field. The candidate has extensive knowledge of and experience in with statistical methods and computational approaches to analyze large, multi-omic datasets using appropriate software including R and Python. The candidate is able to conduct independent research and analysis as evident from a track record of competitive publications and open repositories with analysis methods (such as on Github). We expect the candidate to demonstrate professional competences in team science, show the ability to effectively communicate with collaborators and occasionally present oral communication to large groups; the candidate is conscientious and efficient in meeting commitments, observing deadlines, and achieving results. The candidate has ample experience with quantitative research, (big) data analysis, and is proficient in English writing.
€5504 per month
Groningen, Groningen
Thu, 03 Oct 2024 02:05:13 GMT
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