PhD Student researcher (R1) on metastatic breast cancer models European Research Council Consolidator Grant – DORMATRIX Bioengineering in Regeneration and Cancer Group

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PhD Student researcher (R1) on metastatic breast cancer models European Research Council Consolidator Grant – DORMATRIX Bioengineering in Regeneration and Cancer Group

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Job description

Offer DescriptionPhD Student researcher (R1) in the field of Biomedicine, Biology, Biochemistry, Biophysics or similarThe Cipitria Lab – Bioengineering in Regeneration and Cancer at Biogipuzkoa Health Research Institute, San Sebastián-Donostia, Spain ( ) is looking for a postdoctoral or PhD researcher. In our group, we aim to understand how biophysical and biochemical properties of native extracellular matrix and synthetic biomaterials guide cell response in regeneration, cancer dormancy and bone metastasis. Biogipuzkoa is located within the structure University Hospital Donostia-Onkologikoa.Funded by an ERC CoG grant ( ), the main objective of DORMATRIX is to engineer breast cancer dormancy as a collective emergent phenomenon using biomaterials-based dormancy-on-a-chip devices. In this project, you will develop in vivo breast cancer models to visualize early breast cancer metastasis and changes in the tumor microenvironment.Where to apply WebsiteRequirementsResearch Field Biological sciences Education Level Master Degree or equivalentSkills/QualificationsREQUIRED-PhD or MSc in Biomedicine, Biology, Biochemistry, Biophysics or similar-Previous experience in the biomedical field, cell biology or cancer biology labs will be an asset-Previous experience with in vivo models and FELASA certificate will be an asset-Excellent ability to conduct experiments independently and collaboratively within our group-Keen interest in multidisciplinary work, collaborative mindset and motivation to work in an international environment-Strong organization skills, project management and proactive “getting things done” mentality-Interest to learn and grow professionally in a young, dynamic and competitive lab-Have a genuine excitement for science, innovation and creative thinking!-Good written and oral communication skills in English (Spanish is not required)Specific RequirementsYour tasks:-Develop in vivo early metastatic breast cancer models-Perform preclinical in vivo imaging by bioluminiscence-Multi-modal characterization of early breast cancer metastasis and changes in the tumor microenvironment-Participate in advanced 3D imaging, primarily with light sheet fluorescence microscopy (LSFM)-Participate in correlative 3D imaging of tissue structure and biology combining LSFM with high resolution X-ray tomography-Our lab maintains an active part in Germany, as well as interaction with partners at the Max Planck Queensland Center ( ). You will participate in regular consortium meetings and larger consortium eventsSuggested reading:

• Young et al, Science Advances 10, eadj0975 (2024)
• Young et al, Bone 161, 116432 (2022)
• Bakhshandeh, Heras et al, Science Advances, 10, eadr3997 (2024)

Languages ENGLISH Level ExcellentInternal Application form(s) neededApplication Manual for Employment Offers of the Biogipuzkoa Health Research Institute.pdfEnglish(433.44 KB – PDF)Additional InformationBenefitsCONTRACTUAL CONDITIONS

• TYPE OF CONTRACT (LEGAL REFERENCE): PhD contract for 4 years.
• WORK SCHEDULE: full time
• EXPECTED START DATE: Sept-Oct 2025
• ANNUAL GROSS SALARY:

• PhD researcher: from 20.808€ gross per year, with annual progression

The remuneration shall be based on the candidate’s commitment and merit, as well as how suited they are for the role. The worker must comply with the operating rules set by the Biogipuzkoa Institute in terms of commitment, duties, working hours, leave entitlements, etc.Eligibility criteriaEVALUATION (MAXIMUM OF 100 POINTS WITHOUT AN INTERVIEW AND 125 POINTS WITH AN INTERVIEW)Only applications that meet the REQUIRED competencies in the offer shall be taken into account.

• EXPERIENCE (75 POINTS)
• PROVEN LANGUAGE SKILLS (10 POINTS)
• OTHER DISTINCTIONS (5 POINTS)
• CERTIFICATE VERIFYING A MINIMUM DISABILITY OF 33% (0-10 POINTS)
• INTERVIEW (0-25 POINTS)

Selection processCandidates MUST apply for the offer through the job portal of the IIS Biogipuzkoa website: . Do not submit documents in paper form. All documents must be submitted electronically via the website .For the application, please send in a single PDF of maximum size 5 MB (i) a motivation letter describing your experience, research interests, expectations and preferred start date, (ii) your CV with a complete list of publications, (iii) transcript of university record and (iv) contact information for three references, to: and , indicating “DORMATRIX – Postdoc or PhD in vivo cancer model” in the subject line. The position will remain open until filled.BIOGIPUZKOA is committed to the principles of open, transparent and merit-based recruitment (OTM-R policy), in accordance with the requirements of the HRS4R seal established by European Commission.As such, it takes responsibility for ensuring gender equality based on the goals established in the current Gender Equality Plan.Once the evaluation and selection have been conducted, candidates may request information on their scores, as well as the score of the selected candidate.For any questions/clarification related to this job, please e-mail and .CV submission deadline: 31/05/2025Website for additional job detailsWork Location(s)Number of offers available 1 Company/Institute ASOCIACIÓN INSTITUTO DE INVESTIGACIÓN SANITARIA BIOGIPUZKOA Country Spain State/Province GUIPUZCOA City SAN SEBASTIAN Postal Code 20014 Street PASEO DR. BEGUIRISTAIN S/NContact State/ProvinceGipuzkoa CitySan Sebastian WebsiteStreetPaseo Dr. Beguiristain Postal Code20014 E-Mailarantza.abad@biodonostia.orgSTATUS: EXPIREDShare this page

Expected salary

€20808 per year

Location

San Sebastián, Guipúzcoa

Job date

Fri, 04 Apr 2025 01:47:21 GMT

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