University Hospital of Würzburg (UKW)
PhD Student (Doktorand/in) in CAR T cell Engineering for Cancer Immunotherapy (m/f/d)
Our research focuses on the development and clinical translation of adoptive cancer immunotherapy with T cells that have been modified by gene transfer to express chimeric antigen receptors (CARs). CAR T cell therapy is a transformative treatment in cancer medicine and the PhD students desired for this project will have the ability to make a contribution to this transformation.
Several positions are open with focus on handling the challenges of hard-to-treat cancers in ex vivo and in vivo models. The projects are embedded in a transnational and multidisciplinary consortium of experts with complementary expertise, coordinated by the Medizinische Klinik und Poliklinik II, to join forces in overcoming the tumor heterogeneity and immunosuppressive tumor microenvironment in solid tumors and multiple myeloma, discovering novel targets and advancing gene transfer technologies.
The project is based on chimeric antigen receptor (CAR) T cell genetic engineering with in-depth functional analyses in vitro, ex vivo and in vivo.
The project is highly visible, high risk/high gain and can serve as the kickstarter for an excellent scientific career. The Program is designed for a 3-year period and can start immediately (from April 2023). Salary is paid according to the German public service scale based on candidates’ background and experience (TV-L).
Applicants for this position should have or be about to obtain their master’s degree in biomedicine, biology, biochemistry, or a related field with excellent result, have expertise in (T cell) immunology, gene editing/ engineering, ideally also mouse tumor models and molecular biology. Key characteristics of successful applicants will include a high level of enthusiasm, result oriented work style, analytical thinking, excellent communication and time management skills and the ability to face scientific challenges with creativity and dedication.
Disabled applicants will be considered preferentially in case of equivalent qualifications.
[email protected] & [email protected]
Medizinische Klinik und Poliklinik II – Hämatologie/Onkologie,
Lehrstuhl für Zelluläre Immuntherapie,
Dr. rer. nat. Maik Luu & Prof. Dr. Michael Hudecek
Versbacher Straße 5, Building E4/R 4.03, D-97078 Würzburg, Germany
Dr. Luu, Maik
+49 (931) 201-71297
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