PhD position on cellular self-organization during development
Offer DescriptionWe are recruiting a PhD student with a background in experimental biology to work on self-organization in multicellular systems.
In our lab, we use C. elegans embryogenesis as a model to understand how cells can achieve near-invariant positioning as they form a complex multicellular system. In this project, you will use quantitative microscopy to probe the embryo and perturb the system, for example with temporal and spatial resolution using optogenetics. Our research aims to identify new relevant molecular actors involved in positioning, and to explore the role of mechanics, cellular stiffness, adhesion and cell polarization. The research in our group is multidisciplinary, meaning that experiments and imaging are supported by efforts to expand the molecular biology toolbox, enhance image processing and computational modeling. We also plan to extend our work to include organoid systems for studying early embryogenesis in higher animals in the near future.
The specific content of the PhD project will be developed collaboratively during the first months, with guidance and support from the team. Potential research questions may include optogenetic perturbation of cortical tension during morphogenesis, evaluating mechanosensing in the embryo, or performing an innovative reverse genetic screen for robust cellular positioning. As a member of our team, the successful candidate will have the opportunity to work with state-of-the-art microscopy and computational tools and collaborate with experts in the field.Where to apply WebsiteRequirementsResearch Field Biological sciences Education Level Master Degree or equivalentResearch Field Engineering Education Level Master Degree or equivalentLanguages ENGLISH Level GoodResearch Field Biological sciences Years of Research Experience NoneAdditional InformationBenefits
Eligibility criteria
Selection processFor further information you can contact Rob Jelier: .
You can apply for this job no later than 08/07/2024 via theWork Location(s)Number of offers available 1 Company/Institute KU Leuven Country Belgium State/Province Vlaams Brabant City Leuven Postal Code 3000 Street Leuven GeofieldContact State/ProvinceLeuven CityVlaams Brabant StreetLeuven Postal Code3000 E-Mailrob.jelier@kuleuven.beSTATUS: EXPIREDShare this page
Louvain, Brabant Flamand
Sun, 16 Jun 2024 23:54:02 GMT
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