PhD Position

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PhD Position

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Job description

In het kort–3.017 – 3.82432 – 36 uurWOGeplaatst op 30 oktober 2024Reageren kan t/m 30 november 2024De link om te solliciteren staat in de vacaturetekst.Longziekten en TuberculoseWorking EnvironmentThe PhD student will be working within the department of Pulmonary Diseases and Tuberculosis of the UMCG. The research will be embedded within the Groningen Research Institute for Asthma and COPD (GRIAC), a multidisciplinary and highly translational research institute performing fundamental and applied patient-related research with the aim to unravel underlying mechanisms of the development and progression of lung diseases, including asthma, COPD and pulmonary fibrosis.The project is part of a national consortium, where there will be close collaboration with the department of Cardiothoracic Surgery (dr. Erasmus) and Pathology & Medical Biology (Prof. dr. Heijink, Prof. dr. Brandsma and Prof. dr. Nawijn), and laboratory of Experimental Pulmonology and Inflammation Research (EXPIRE). Within these departments multiple renowned research groups work on pathophysiological damage and repair processes, using translational and multi-omic approaches (transcriptomics e.g. single cell RNA sequencing, proteomics etc), and state-of-the-art cellular and molecular techniques, to obtain insights into novel therapeutic strategies. In addition there will be a close collaboration with the consortium partners from University of Groningen (Prof. dr. Gosens), Twente University (Prof. dr. Leijten and Prof. dr. Prakash) and University Medical Center Leiden (Dr. van der Does, Prof dr. Hiemstra and Prof. dr. J.J. Zwaginga).Job descriptionThe PhD student will participate in research which is part of the Netherlands Research Council (NWO)-funded consortium that aims to develop a locally administered regenerative cell therapy for tissue restoration in chronic obstructive pulmonary disease (COPD). This is a prevalent inflammatory disease characterized by irreversible airflow obstruction. The disease has high morbidity and mortality, being the third leading cause of death worldwide. The tissue damage in COPD is severe and irreversible. Therefore, there is an urgent need for regenerative cell therapy for tissue restoration in COPD.Within the UMCG, the PhD student will work with the ex vivo lung perfusion model where the main focus will be optimization of the model for administration of regenerative therapies developed within the RecovAir consortium. The ex vivo lung perfusion will be performed in cadaveric animal lungs and human explanted COPD lungs. In addition, further studies will be performed on deposition/distribution and engraftment of regenerative cells after the initial optimization.Requirements– You have a Master’s degree in the Molecular/Medical Biology or Biomedical Sciences field with a strong drive to further develop in this area.
– You can work independently but you are also a team player.
– You have experience with cellular and molecular models in the lab, such as qPCR.
– You are enthusiastic and curious about experimental research and have affinity for fundamental and translational research.
– You are highly motivated, self-confident and pro-active.
– You have excellent organizational, communication and interaction skills, along with strong project- and time management skills.
– Command of the English language in spoken and written word is mandatory.

TThe UMCG has a preventive Hepatitis B policy. The UMCG can provide you with the vaccination, should it be required for your position. In case of specific professions a ‘Certificate of Good Conduct’ is required.Conditions of employmentWe offer a 4 year PhD position for 32 to 36 hours per week, with a go/no-go decision after 12 months. Your salary will be a maximum of € 3.824,- gross per month (scale PRO), depending on your qualifications and relevant experience, based on a full-time appointment. In addition, the UMCG will offer you 8% holiday pay, and 8.3% end-of-year bonus. The conditions of employment comply with the .Additional informationFor more information about this vacancy you may contact:dr. Roland Hoffmann 050 361 2851
dr. Tji Gan 06 2565 0198Applying for a jobSolliciterenPlease use the the digital application form at the bottom of this page – only these will be processed. You can apply until 1 December 2024. Within half an hour after sending the digital application form you will receive an email- confirmation with further information.In het kort–3.017 – 3.82432 – 36 uurWOGeplaatst op 30 oktober 2024Reageren kan t/m 30 november 2024De link om te solliciteren staat in de vacaturetekst.UMCGWaar staat UMCG voor? Wat vinden ze belangrijk? Ontdek het hier.Vacature delen of bewaren?Deel de vacature op social media of met je vrienden. Later solliciteren? Geef een hartje en je vindt hem makkelijk terug.Bewaren DelenBen jij de match?Zorg er dan voor dat jouw sollicitatie uiterlijk 30 november 2024 bij ons binnen is. Reageren kan via de sollicitatiebutton, dus het is snel voor elkaar. Heb je vragen over inhoud van de functie? Neem dan contact op met de organisatie.Ontdek meerGerelateerde vacaturesAl gesolliciteerd?Eerder door jou bekekenPhD Position

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Expected salary

€3824 per month

Location

Groningen, Groningen

Job date

Sat, 02 Nov 2024 03:13:11 GMT

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