PhD fellowship in Microbiology and Immunology
Københavns Universitet
We are offering a fully funded PhD fellowship in Microbiology and Immunology commencing 1 May 2025 or after agreement.Our group and research
The Parasites, Immunology and Gut Health (PIGH) group applies animal models and in vitro cell culture techniques to explore host-pathogen-microbiome interactions and nutritional immunology. The group is a multidisciplinary team embedded within the Department of Veterinary and Animal Sciences, with close links to other sections working on diseases, food chemistry, natural product chemistry, and the gut microbiome. Our aims are to develop novel therapies to prevent infection and disease in animals and humans. The group is international in nature, and the daily working language is English.Project descriptionThe role of nutrition and dietary components in regulating mucosal immune function is becoming a new and exciting research area. Our group is interested in how dietary components and the gut microbiota interact to regulate immunity at mucosal surfaces, which is critical for protection against pathogens but can also cause pathologies such as IBD when dysregulated.The PhD project will focus on polyphenols, a class of common dietary compounds with putative health benefits. We aim to determine how polyphenols interact with gut bacteria to produce metabolites with immunomodulatory activity. We will use molecular microbiology, transcriptomics, and gene editing to uncover metabolic pathways involved in polyphenol breakdown. Finally, we will use mouse models of bacterial and parasitic infection to determine if synbiotic treatment with polyphenols and defined bacteria enhances mucosal immunity to infection. Full training will be provided. The PhD student will also contribute to teaching in the section.The project is a collaboration with the Phage and Quorum Sensing group lead by Associate Professor Nina Molin Høyland-Kroghsbo at the Department of Plant and Environmental Sciences, and the PhD student will work in both research groups. Moreover, the project will involve an international stay of several months at the University of California, Davis, USA, which will take place at the beginning of the PhD.Principal supervisor is Associate Professor Andrew Williams, Department of Veterinary and Animal Sciences. +45 3138 3122Start: 1 May 2025Duration: 3 yearsJob description
Your key tasks as a PhD student at SUND are:
Key criteria for the assessment of applicants
Applicants must have qualifications corresponding to a master’s degree related to the subject area of the project, e.g. Microbiology, Immunology, Biology, Biotechnology. Please note that your master’s degree must be equivalent to a Danish master’s degree (two years).Other important criteria are:
Place of employmentThe place of employment is at the Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and facilities for experimental animal studies.Terms of employment
The average weekly working hours are 37 hours per week.The position is a fixed-term position limited to a period of 3 years. The start date is 1 May 2025 or after agreement.The employment is conditioned upon the applicant’s successful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.
København
Thu, 12 Dec 2024 08:21:06 GMT
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