PhD fellow in human stem cell biology and metabolism

Job title:

PhD fellow in human stem cell biology and metabolism

Company:

Københavns Universitet

Job description

The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW) at Faculty of Health & Medical Sciences at the University of Copenhagen is looking for a PhD fellow to join the Żylicz group starting September 2024 or upon agreement with the chosen candidate.The Center:The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW has its Hub at the University of Copenhagen (UCPH) as well as nodes at UCPH, Murdoch Children’s Research Institute and Leiden University Medical Center. Researchers within reNEW addresses fundamental questions in stem cell and developmental biology and will pivot research findings to clinical outcomes and products.The position as PhD fellow is for 3 years.Our researchA PhD position is available in the group of Jan Żylicz at reNEW. The team studies fundamental mechanisms of early mammalian development and stem cell biology. The Żylicz group wants to understand how metabolic and epigenetic mechanisms cooperate to regulate transcription during early development. In particular the team is interested in how metabolism regulates histone modifiers, and how these in turn affect lineage choice and embryo growth at around the time of implantation. To achieve this, the group utilizes both in vivo mouse models as well as in vitro human stem cell culture systems and state-of the-art ultrasensitive transcriptomic, epigenomic and metabolomic techniques. This PhD project will combine these methods with biochemical and mechanistic analysis in human 2D and 3D stem cell models. Starting date for this position is the 1 September 2024, or upon agreement with the chosen candidate.Job description:We are seeking a highly motivated and ambitious pre-doctoral candidate with a strong educational background in human stem cells and developmental biology. The candidate will investigate the molecular mechanisms controlling first lineage choice of early development using both in vivo and in vitro stem cell models.Qualifications:

• Candidates must hold a master’s degree in biotechnology, bio-informatics, biology or similar, and possess a strong background in developmental and stem cell biology.
• Previous practical experience with work on human naïve embryonic stem cells and mammalian embryos is a requirement.
• Practical project experience in basic lab techniques is necessary.
• Good English communication skills, both oral and written, are prerequisite for the successful candidate.
• A solution-oriented, organizational and positive mindset is required. The ability to work in a highly diverse and collaborative environment both independently and as part of the team is essential.

Terms of salary, work, and employment :The employment is for 3 years, and is scheduled to start in September 2024 or upon agreement with the chosen candidate. The employment as a PhD student is conditioned upon a positive assessment of the candidate ‘s research performance and enrolment in the Graduate School at the Faculty of Health and Medical Sciences.The PhD study must be completed in accordance with the ministerial orders from the Ministry of Education on the PhD degree and the University ‘s rules on achieving the degree.

The place of work is at reNEW, University of Copenhagen, Blegdamsvej 3B, Copenhagen. Salary, pension and terms of employment are in accordance with the provisions of the collective agreement between the Danish Government and AC (the Danish Confederation of Professional Associations). In addition to the basic salary a monthly contribution to a pension fund is added (17.1% of the salary).The application must include: * Motivation letter

• Curriculum vitae incl. education, experience, previous employments, language skills and other relevant skills
• List of two references (full address, incl. email and phone number)
• Copy of diplomas/degree certificate(s) your master’s degree must be equivalent to a Danish master’s degree.

Questions:For further information contact Associate Professor Jan Żylicz, .How to applyThe application, in English, must be submitted electronically by clicking APPLY below.The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background.Only applications received in time and consisting of the above listed documents will be considered.Applications and/or any material received after deadline will not be taken into consideration.The application will be assessed according to the Ministerial Order no. 284 of 25 April 2008 on the Appointment of Academic Staff at Universities.Assessment procedureAfter the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself. You can read about the recruitment process atApplication deadline: 7 June 2024We want to reflect the surrounding society and encourage all qualified persons, regardless of personal background, to apply for the position.Founded in 1479, the University of Copenhagen is the oldest university in Denmark. It is among the largest universities in Scandinavia and is one of the highest ranking in Europe. The University´s eight faculties include Health Sciences, Humanities, Law, Life Sciences, Pharmaceutical Sciences, Science, Social Sciences and Theology.Københavns Universitet giver sine knap 10.000 medarbejdere muligheder for at udnytte deres talent fuldt ud i et ambitiøst, uformelt miljø. Vi sikrer traditionsrige og moderne rammer om uddannelser og fri forskning på højt internationalt niveau. Vi søger svar og løsninger på fælles problemer og gør ny viden tilgængelig og nyttig for andre.

Expected salary

Location

København

Job date

Sat, 25 May 2024 22:52:39 GMT

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