Nonclinical Drug Development (Senior) Scientist
ProQR Therapeutics
ProQR Therapeutics is a biotechnology company listed on NASDAQ with offices in Leiden, the Netherlands and Cambridge, Massachusetts, USA. ProQR is focused on the development of life changing RNA therapies to meet the unmet need of individuals and families with common and rare diseases. A team of 150+ enthusiastic ProQRians from all walks of life and more than 30 different nationalities is up to this challenge. We have the passion and commitment to make a difference in the lives of the communities we serve. Our proprietary Axiomer® RNA editing technology platform enables the editing of specific single nucleotides in RNA using the cells own editing machinery. Axiomer® RNA editing technology harnesses ADAR (Adenosine Deaminase Acting on RNA), which is machinery present in all human cells to repair G-to-A mutations, modulate protein, and enable protective mutation functions. Axiomer could potentially yield a new class of innovative medicines and treat currently untreatable diseases.ProQR is currently recruiting a Nonclinical Drug Development Expert (Scientist/ Senior Scientist) with expertise in Toxicology and ADME to join the Translational Development team, that works in a highly collaborative fashion in Discovery and Clinical Development on in vivo pharmacology studies, in vitro and in vivo safety studies, bioanalysis, pharmacokinetics and biomarkers. In your role, you will be reporting to the VP Toxicology and DMPK / Head Preclinical Team.Location: Leiden, NLThe role:ProQR is looking for an allround nonclinical subject matter expert who will be responsible for the design and monitoring in vivo studies (through selected vendors), evaluation of data, and development of PKPD/disease models in our research and development programs. Studies will range from pharmacology to toxicology (ICH/GLP). The successful candidate is an enthusiastic and creative team player and will work closely with other colleagues in an interdisciplinary team environment to progress the translational science in ProQR’s programs.The activities include:
Required qualifications:
ProQR as an employerAs an employer, we are a true believer of the value of a workforce in which people from diverse backgrounds are encouraged to develop themselves, personally and professionally. We believe that happy and energized people, working well together in an environment in which they thrive, will do phenomenal and awesome things.We are committed to ensure that no employee, candidate or job applicant receives less favorable treatment on the grounds of race, age, disability, pregnancy, religion, gender identity and expression, sexual orientation, marriage or civil partnership status. At ProQR we want to create an inclusive culture where everyone can be valued for who they are and in which individual differences and the contributions in all forms are recognized and valued.We offer an exciting and innovative working environment in a very committed organization, with the following benefits:
Do you think you can contribute in achieving our mission? If so, we’re looking forward to receiving your application by filling out our application form.You can contact Silvia Catellani via if you have any questions.
Leiden, Zuid-Holland
Sat, 14 Dec 2024 23:22:46 GMT
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