Chercheur(se) Post-Doctorant(e) sur la régulation de la latence du VIH (Spécialiste en génomique) Post-Doctoral Researcher on HIV latency regulation (Genomics specialist)
Offer DescriptionPrès de 40 millions de personnes dans le monde vivent avec le VIH, et un obstacle majeur à son éradication est la persistance du virus dans un état latent au sein des cellules réservoirs. Notre groupe de recherche à l’Institut Cochin se spécialise dans la compréhension de l’établissement et du maintien de la latence du VIH-1 dans les cellules CD4+ infectées. Nous avons récemment identifié plusieurs voies impliquant des facteurs épigénétiques et de métabolisme de l’ARN de la cellule hôte, qui conduisent au silence du VIH-1 aux niveaux transcriptionnel et post-transcriptionnel.
Nous recherchons un(e) Postdoctorant(e) motive(e) pour comprendre comment ces mécanismes de repression d’expression virale sont mis en place conduisant à la latence du VIH-1.Activités PrincipalesConduire et mener ses activités de recherches sur le plan intellectuel et experimental.
Almost 40 million people worldwide live with HIV, and a major obstacle to its eradication is the virus’s persistence in a latent state within reservoir cells. Our research group at Institut Cochin specializes in understanding how HIV-1 latency is established and maintained in CD4+ infected cells. We have recently identified several pathways involving host cell epigenetic and RNA metabolism factors that lead to HIV-1 silencing at both the transcriptional and post-transcriptional levels.
We are seeking a highly motivated Postdoctoral Fellow to characterize one of these critical pathways at the RNA/Chromatin interface, which has been shown to be essential for HIV-1 silencing.Main Activities :Conduct and carry out research activities on both intellectual and experimental levels.
Where to apply E-mailroy.matkovic@inserm.frRequirementsResearch Field Biological sciences » Biology Education Level PhD or equivalentSkills/QualificationsConnaissances / Expertise :
Savoir-faire / Know-how :
Aptitudes / Ability :
Specific Requirements
Languages ENGLISH Level ExcellentAdditional InformationWork Location(s)Number of offers available 1 Company/Institute Institut Cochin Country France State/Province Ile-de-France City Paris Postal Code 75014 Street 22 rue Mechain GeofieldContact CityParis WebsiteStreet88 rue Regnault Postal Code75013STATUS: EXPIREDShare this page
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Sat, 03 Aug 2024 02:30:39 GMT
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