Postdoc – Advanced Process Control

Job title:

Postdoc – Advanced Process Control

Company:

Johnson & Johnson

Job description

Post Doc – Advanced Process ControlLocation: Leiden, NetherlandsStart Date: ASAPAt Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more atWe are looking for a motivated and driven Postdoctoral Scientist to join our team in an innovative automated process control project within cell culture manufacturing. In this role, you will play a key part in developing and implementing sophisticated automation strategies for biologics drug substance production, with a strong emphasis on modeling and process control. You will collaborate closely with the Leiden site and the Global Process Science Modeling & Data teams to demonstrate the potential of model-based feedback control in revolutionizing cell culture processes.Join us in shaping the future of biologics manufacturing and advancing the next generation of cell culture technologies!Key Responsibilities:

• Design mechanistic models to accurately capture the behavior of various cell lines in cell culture processes
• Infer key model parameters’ values from data
• Design a model-based feedback control loop to dynamically optimize critical process parameters in real-time under hard and soft constraints
• Partner with industry and academia to validate the developed models and control strategy
• Work multi-functionally with internal teams to efficiently implement the designed control strategy
• Present findings and innovations at internal meetings and external scientific conferences

Qualifications

• PhD in a STEM field (e.g. Chemical Engineering, Physics, Computer Science or other relevant subject area)
• A strong background in mechanistic modeling and optimization techniques
• A strong background in model-based process control and state estimation techniques
• Proficiency in scientific programming with Python and familiarity with Process Analytical Technology (PAT) tools and sensors
• Familiarity with Bayesian modeling is a plus
• Previous exposure to cell culture manufacturing in a pharmaceutical setting is a plus
• Outstanding ability to identify, analyze, and proactively and independently address potential challenges
• Excellent communication and teamwork skills and ability to work optimally within multi-functional teams

For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.At Johnson & Johnson, we all belong.#JNJEMEAStudentCareers #JNJEMEAFullTime

Expected salary

Location

Leiden, Zuid-Holland

Job date

Fri, 20 Dec 2024 05:35:00 GMT

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