Research Associate / Senior Research Associate in Evidence Synthesis

University of Bristol

Job title:

Research Associate / Senior Research Associate in Evidence Synthesis

Company:

University of Bristol

Job description

Salary:Grade I: £37,099 – £43,878;Grade J: £42,632 – £47,874 per annumThe roleThis post provides an exciting opportunity for a talented statistician to contribute to the development of impactful statistical methodology and to healthcare policy. You will contribute to developing methods for Multilevel Network Meta-Regression (ML-NMR), combining evidence from multiple trials with mixtures of individual participant & aggregate data, in order to produce population-adjusted estimates of treatment efficacy. These methods are increasingly prevalent in health technology assessment, and are used by manufacturers making submissions to regulators such as the National Institute for Health and Care Excellence (NICE). You will apply this methodological work & gain expertise in wider evidence synthesis methods by joining the Bristol Technology Assessment Group (TAG), which is contracted by the NIHR to conduct independent reviews of healthcare technologies, supporting the NICE guidance committees and other policy makers. Bristol is a centre for methodological excellence in evidence synthesis and health technology assessment, having developed many of the methods used as standard practice in NICE technology appraisals.What will you be doing?You will contribute to methodological development of the ML-NMR framework, developing extensions to use information from subgroup analyses or regression coefficients, and to handle issues such as missing data & treatment switching. You will design & analyse comprehensive simulation studies to assess the performance of these methods using the University’s high performance computing cluster, and contribute to the development of R packages to implement these methods. You will work as part of a multidisciplinary team in the Bristol TAG to contribute to the review of technology appraisals, subjecting manufacturer submissions to rigorous critique of their statistical analyses and conducting analyses under a range of alternative assumptions. You will be provided with training and development to ensure you have the skills necessary for this role and to stay up to date with the latest methodologies. There will be opportunities for you to contribute to teaching and research proposals, and you will be encouraged and supported to develop your own research interests over the course of the post.You should apply if

  • You have training & experience in statistical modelling, including likelihoods, generalised linear models, & fixed vs random effects
  • You have experience of coding in at least one statistical language, such as R, Python, or Stata
  • You have training or experience of meta-analysis
  • You have an interest in the development and application of advanced statistical methods
  • You have an interest in health technology assessment and an enthusiasm to contribute to NICE technology appraisals
  • You work well independently and as part of a multidisciplinary team
  • You have a relevant Masters degree
  • You have a relevant PhD (or working towards one), or equivalent research experience, if applying for Senior Research Associate

Additional informationContract type: Open-ended with funding until 31/10/2026For informal queries please contact: David Phillippo,Our strategy and missionWe recently launched our to 2030 tying together our mission, vision and values.The University of Bristol aims to be a place where everyone feels able to be themselves and do their best in an inclusive working environment where all colleagues can thrive and reach their full potential. We want to attract, develop, and retain individuals with different experiences, backgrounds and perspectives – particularly people of colour, LGBT+ and disabled people – because diversity of people and ideas remains integral to our excellence as a global civic institution.£37,099 to £47,874. Grade I/J, per annum

Expected salary

£37099 – 47874 per year

Location

Bristol Area

Job date

Wed, 16 Oct 2024 00:02:57 GMT

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