Postdoc in Synthetic Biology

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Postdoc in Synthetic Biology

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Job description

Offer DescriptionWhat: A full-time postdoc contract of up to 4 years to engineer synthetic gene circuits.
Where: University Pompeu Fabra, Barcelona, Spain.
When: Deadline: 15th Nov 2024 or until filled – Start: 1st Dec 2024 or when agreed.Description:
The emerging ‘Synthetic Cell Programming’ lab, led by Dr. Santos-Moreno ( ),is seeking for a highly-motivated postdoctoral researcher for engineering synthetic gene circuits to program time in E. coli cells. This position is funded by an ERC Starting Grant (project: TICK-TOCK Do and Die).Past achievements of Dr. Santos-Moreno include tool development for synthetic biology, such as CRISPRi-based circuits ( ) or modular cloning approaches ( ); the use of those tools to address longstanding biological questions, related to evolution ( ) or pathogenesis (Rueff et al. 2023, Nat Commun); and the engineering of diverse members of the human microbiome – including gut (E. coli), lung (S. pneumoniae, in collaboration) and skin (C. acnes) microbes – for basic or applied research, such as the delivery of molecules with anti-acne potential by an engineered skin bacterium ( ).The group is part of the Medicine and Life Sciences ( ) department at the University Pompeu Fabra (UPF), a high-class institution with demonstrated competitiveness. The lab is physically located at the Biomedical Research Park of Barcelona ( ), a multidisciplinary bio-hub with state-of-the-art facilities hosting top-class research institutes, including the Center for Genomic Regulation (CRG), and the European Molecular Biology Laboratory (EMBL), among others. You will benefit from a stimulating and international research environment in a young and dynamic team. The host group is committed to maintaining a respectful, inclusive, and friendly working environment for all staff and students, as well as promoting personal and career development.Your role:
You will work on designing and building synthetic gene circuits to program time in E. coli cells, using CRISPRi, transcription factors, and other molecular tools. Following the in silico design, you will construct the circuits using advanced cloning techniques and you will evaluate their performance using microplate reader measurements, flow cytometry and fluorescence microscopy, among other techniques. After building and characterizing prototype circuits, you will fine-tune them and connect them to other circuits / actuator modules.You are also expected to write articles, present results at seminars / conferences, contribute to the training of PhD candidates and undergraduate students, collaborate with other group members and labs, and apply for postdoc fellowships. If interested, you can also participate in teaching and outreach activities.How to apply:
Please send your application to with ‘Postdoc timers Nov’ as the subject line. Provide your ID/Passport number in the body of the email, and include all of the following in a single PDF document named as ‘Postdoc-timers-Nov_yourName_yourSurname.pdf’: * Motivation letter

• CV, including a publication list
• Contact details of 3 references

Questions?
Please contact Javier Santos-Moreno ( ) for inquires.Where to apply E-mail[email protected]RequirementsResearch Field Biological sciences Education Level PhD or equivalentSkills/Qualifications

• High motivation and proactivity
• Ability to work independently and as part of a team
• Strong organizational skills
• Scientific integrity and rigor
• A good command (spoken & written) of English language

Specific Requirements1) A PhD in life sciences.
2) One or more 1st-author publications in major peer-reviewed international journals.
3) Experience:

• Essential: strong background in wet-lab synthetic or molecular biology.
• Highly desirable: experience in designing gene circuits or in modelling them.
• Desirable: experience in bacterial cultivation, microfluidics, dynamic systems, synthetic memory, or biocontainment.

Additional InformationBenefits

• A full-time postdoc contract of up to 4 years.
• Competitive salary.
• 36 days/year of paid holidays: 22 days of personal choice + 14 bank holidays.
• Full access to the Spanish national social security, including free-of-charge access to the health system and unemployment and retirement contributions.
• Measures to reconcile work & family life, including parental leave and flexible working hours.
• Mentorship and training, including access to free courses and resources, to accelerate your professional development.

Work Location(s)Number of offers available 1 Company/Institute Universitat Pompeu Fabra Country Spain State/Province Barcelona City Barcelona GeofieldContact CityBarcelona WebsiteStreetDr. Aiguader, 88 Postal Code08003STATUS: EXPIREDShare this page

Expected salary

Location

Barcelona

Job date

Fri, 11 Oct 2024 05:39:50 GMT

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