Postdoctoral fellow – RNA therapeutics

Job title:

Postdoctoral fellow – RNA therapeutics

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Job description

Offer DescriptionThe Fortes lab at CIMA (University of Navarra, Spain) is looking for a postdoctoral student with a molecular biology background and skills in RNA biology to investigate the interplay between DNA damage and functional non-coding RNAs.The Fortes lab ( ) aims to develop biotechnological tools based on natural long non-coding RNAs and derived microproteins or on artificial non-coding sequences. We work to deliver these novel RNA therapeutics into tumor cells with a special focus on hepatocellular carcinoma. We have a network of outstanding collaborators to expand our expertise from the bench to preclinical models and to the clinical setting.Your roleThe successful candidate will work on a cutting-edge experimental research project that moves from single molecule studies performed in close collaboration (AFM, cryo-EM, magnetic tweezers, C-trap), and genetic evolution (SELEX) or identification of natural lncRNA mimics with novel high-throughput technology to cellular validations and preclinical models. The goal of the project is to contribute with exquisite technology with translation potential to the future understanding of the RNA code: the set of rules that link RNA sequence with structure and function.The complete project involves a combination of molecular biology, biophysics, and structural biology. This project is in close collaboration with Fernando Pastor (also at CIMA), Oscar Llorca (CNIO, Madrid) and Fernando Moreno-Herrero (CNB, Madrid), and will involve regular communication and scientific exchange with the collaborators.You have

• PhD in molecular biology, biochemistry, or related disciplines (or close to finishing PhD).
• Pasion for science. Strong interest in the research topic, high motivation and commitment
• Experience with RNA and high throughput studies, cell culture techniques and wiliness to work with preclinical models.
• Ability to work independently and creatively coming up with innovative solutions to complex scientific problems, in an international team with a highly collaborative atmosphere.
• Excellent in writing, communication and presentation skills. Fluency in English.

You might also have

• Experience with SELEX, CUT&RUN or RADICLSeq
• Expertise in DNA damage
• Experience in data analysis (R, Python).

Closing date: 31 August 2024Initial contract duration: 2 yearsTo Apply:Send an e-mail to with: * Resume or CV. Include 3 names and e-mail addresses for recommendation letters.

• Cover Letter stating why you are interested in this challenge and how you might help the Project to succeed.

Where to apply E-mail[email protected]RequirementsResearch Field Biological sciences Education Level PhD or equivalentAdditional InformationWork Location(s)Number of offers available 1 Company/Institute Center for Applied Medical Research Country Spain GeofieldContact State/ProvinceNavarra CityPamplona WebsiteStreetPio XII, 55 Postal Code31008 E-Mail[email protected]STATUS: EXPIREDShare this page

Expected salary

Location

Pamplona, Navarra

Job date

Sat, 27 Jul 2024 05:34:40 GMT

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